Correction: Decarboxylative Csp3–Csp3 coupling for benzylation of unstable ketone enolates: synthesis of p-(acylethyl)phenols
نویسندگان
چکیده
منابع مشابه
Ruthenium-catalyzed stereospecific decarboxylative allylation of non-stabilized ketone enolates.
The ruthenium-catalyzed stereospecific decarboxylative allylation of ketone enolates provides access to gamma,delta-unsaturated ketones with good yields and enantio-enrichments.
متن کاملLewis acid/CpRu dual catalysis in the enantioselective decarboxylative allylation of ketone enolates.
The addition of a Lewis acidic metal triflate salt Mg(OTf)(2) as co-catalyst in the CpRu-catalyzed decarboxylative allylation of in situ-generated ketone enolates allows the reaction to proceed at lower temperature with higher regio- and enantioselectivity. Even so-far-unreactive substrates react.
متن کاملSynthesis of biaryls via catalytic decarboxylative coupling.
We present a safe and convenient cross-coupling strategy for the large-scale synthesis of biaryls, commercially important structures often found in biologically active molecules. In contrast to traditional cross-couplings, which require the prior preparation of organometallic reagents, we use a copper catalyst to generate the carbon nucleophiles in situ, via decarboxylation of easily accessible...
متن کاملCatalytic Enantioselective Alkylation of Prochiral Ketone Enolates
The synthesis of stereogenic all-carbon quaternary centers remains a formidable challenge, notwithstanding the strides made by modern organic chemistry in this regard [1]. Contemporary advances in enolate alkylation havemade it a fundamental strategy for the construction of C–C bonds [2]. Although methods for the reaction of a number of enolate types (e.g., ester, ketone, and propionimide) with...
متن کاملRecent Progress in Decarboxylative Oxidative Cross‐Coupling for Biaryl Synthesis
The beginning of the 21st century has seen tremendous growth in the field of decarboxylative activation. Benzoic acid derivatives are now recognised as atom-economic alternatives to traditional cross-coupling partners, and they also benefit from being inexpensive, readily available and shelf-stable reagents. In this microreview we discuss recent developments in the coupling of benzoic acid deri...
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ژورنال
عنوان ژورنال: Chemical Communications
سال: 2016
ISSN: 1359-7345,1364-548X
DOI: 10.1039/c6cc90325h